Vitamin D & Your Genes: How VDR Variants Impact Dopamine, Immunity, Aging & Why K2 Isn’t Always Better

Vitamin D is more than a bone-supporting nutrient — it’s a brain, mood, and longevity regulator driven by one key pathway: the Vitamin D Receptor (VDR). For people with VDR gene variants, simply adding more K2 isn’t always beneficial — in fact, it can shift calcium signaling in ways that reduce D3 effectiveness. This article explains how vitamin D affects dopamine, telomeres, and cellular aging — and why personalized supplementation is the key to true vitamin D optimization.